MRI/CT Scanner Cake

Last week I came to the end of a four year physics with medical physics degree, so my project partner of 2 years and I decided to make an MRI scanner cake!

The scanner itself was made from a standard 6oz Victoria sponge recipe, baked in a circle and filled with vanilla buttercream. The cake had a small segment cut off to allow it to stand on the board. The bed of the scanner, we created from a 4oz sponge recipe, baked in a square tin, cut to size and stuck together with buttercream.

Segment removed for standing the cake up
Segment removed for standing the cake up
Making the bed
Making the bed

In order to stick the (bought) royal icing to the cake once rolled, we used apricot glaze – a smooth apricot jam which is melted first before being applied to the cake. It tastes good as well as being practical!

White icing was rolled thinly and then put on the circular cake in stages – the front, back and around the edge – after the cake was stuck to the board with a little buttercream. To hide the joins, and to improve the look of the cake, grey strips were rolled and added around the edges. A bore was created using a circle of black icing (if we’d cut a real hole, there would have been less cake!) on each side of the scanner, made using the top of a wine glass as a template. The bed was covered similarly and was stuck to the board post-icing.

Icing the scanner in stages
Icing the scanner in stages
Rolling out grey icing
Rolling out grey icing

Our little man to be scanned was created from icing, and his dignity conserved with a scrubs-green blanket. Buttons were added using silver balls. This was not difficult to create – although it was definitely useful having 2 pairs of hands for the icing – and went down a treat with those at the Magnetic Resonance Centre!

A happy patient!
A happy patient!

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Physics post – Women in Science

This is an “opinion piece” that I wrote for a module recently. Seeing as I’m not baking at the moment (though I did bake a Bakewell tart for a Christmas present), I thought I’d post some physics-related blogs.

Women in Science: “I Am Not the Exception”

Recent research suggests that there is a difference between men and women’s brains [1]. A recent BBC Horizon episode entitled “Is Your Brain Male or Female?” gave many examples of this. The programme quoted a statistic that men have a 10% larger brain on average than women despite there being no difference in average IQ. Apparently size doesn’t matter. However, there clearly is a physiological difference in brains; it has also been seen that the neural connections in the male and female brain are different. One study has used functional magnetic resonance imaging (fMRI) to study the differences between men and women undertaking a visuospatial navigation task using maze exploration [2]. It was found that men and women use different parts of the brain to navigate (the left hippocampus for men; and right parietal, and right prefrontal cortex for women).

There are other studies that could be quoted to demonstrate the differences between the male and female brain. Whether these dissimilarities are due to nature – hormone fluctuations in the womb; brain size etc. – or nurture – society and pressures from those around us growing up – is a discussion that is ongoing and does not have an answer as of yet. In Horizon, Professor Alice Roberts took the stance that these differences are due to societal pressures and nurture; whilst Dr. Michael Mosley shared his view that there is likely an innate difference between the sexes from (before) birth. I think there is probably a mixture of both nature and nurture causing the variations between the sexes, although I think that the nature aspect is highly important since it is not something we can change and is a fact of life.

Despite this scientific research suggesting differences between male and female brains, society does not seem to want to accept that it may be that men are better – on the whole – than women at certain subjects; whether this be due to innate, “hard-wired” physiological differences or to the environment we are brought up in. Men do significantly better than women in visual spatial tasks, whereas women score higher in emotion-based tests. This, along with many other factors, may begin to explain the differences in subject choice of study between men and women.

In 2010/2011, 53% of people studying at undergraduate level all science subject areas were female. In subjects allied to medicine; veterinary sciences; agriculture and related; biological sciences; and medicine, there was a majority female cohort. However, in mathematical and physical sciences; architecture, building and planning; computer science; and engineering and technology there was a majority male (WISE UK statistics 2012). In 2013, 55.2% of all accepted university applications were to female students (UCAS statistics).
All these statistics can be taken to show that women are not less able than their male counterparts: clearly there is no shortage of women being highly educated, and this is not a debate about academic ability. So why this drive to get women into STEM (science, technology, engineering and mathematics) subjects? Why is there no similar drive to get men into veterinary science; biological sciences or other female-dominated subjects?

The push that we are currently witnessing to get women into STEM subjects makes it seem that there is some urgency and inequality about the situation. The government is even giving funding to try and encourage more women into engineering. Meanwhile, I find it interesting to note that there is no effort to get women onto the building site despite the meagre 6% of women in the building industry.
I would be committing no social faux-pas in commenting on the physical differences between males and females – whether that is anatomically or the general differences such as men tending to be stronger than women. Building is a physically demanding job, and is no doubt one reason that we see more men in the job than women. That is generally an accepted statistic that raises little cause for concern. Yet, for some reason we seem to encounter a problem when a difference is claimed between the brains of men and women; and when that difference is quoted as the reason for difference job choices.

Given the research, no-one is claiming (and if they do they cannot be taken seriously) that one sex is more intelligent than the other – we have already seen that despite differences in brain size there is no average IQ difference, and that in fact more women go to university in the UK than men. There must be some other reason that we regard “women in science” to be an “issue”, and one to be remedied at that.

It seems to me that maths and mathematical studies are held on a bit of a pedestal; perhaps explaining why we hear the term “maths brain” but not “history brain”. If one has an affinity for maths, they are often perceived as very intelligent – more so than someone with an affinity for English, say. Maybe this is because we all speak and use English every day in one sense of the term, but it is no uncertain thing that we do not all possess the talents of Keats, Shakespeare or Malorie Blackman. This “elevation” of the mathematical sciences to a regarded higher intelligence level may give some explanation for why people worry so much about making sure women are “properly” represented in these areas.
On a related note, these subjects tend to be associated with the more highly paid jobs – especially those in the City such as finance. Since there is a large and ever-growing group intent on getting women into exactly “equal” positions to men, they must make sure that women are well-represented in STEM subjects. There is a large desire for the 20% higher salary that men earn to be reduced so that both men and women can earn the same average wage (this is a discussion for another time and involves a lot of controversial issues like women having babies, so I shall say no more on it now).

Another consideration that I would suggest perhaps demands some research of its own is that men may suffer through the initiative to get women into science. Seeing their female contemporaries being actively sought out; given scholarships to take engineering subjects; and given gender-specific careers events, must have some effect on men and their perception of their value within the subject. Every time I receive a “women only” e-mail I wonder if this is fair since I am sure my male counterparts are not treated in this way.

To me, the whole “issue” of women in science (or STEM) is a non-issue. Yes, I am in the minority but no, I am not the exception. I have decided to study a subject (physics) that interests me and presumably, which my brain is suited to. Yet I do not think that young girls need to be pushed into taking up physics, maths or any other subject; and equally, young boys do not need to be encouraged to take English, the biological sciences or anything else. Being a woman has no effect on my status as a physicist, so there is no need to call me a “woman in physics” thank you very much: that clarification is unnecessary and unhelpful.

To conclude, research is definitely showing us that there are differences between the male and female brain – in size and in neural connections. It is also unarguable that men and women are different. Yet the drive to get women in STEM subjects continues with vengeance. I believe this is due to the perceived intellectual nature of mathematical subjects, and the potential monetary advantages linked to these subjects. The statistics show that women in STEM subjects are few but women in other sciences are flourishing in number, and this is no bad thing. Neither men nor women should be pressured into subjects they do not wish to pursue, and there should be no bias in incentives to get them to their end goal. We have been created differently, with brains which appear to function differently. We should embrace this, and be grateful for it.

[1] Ruigrok, A.N.V, Salmimi-Khorshidi, G., Lai, M-C., Baron-Cohen, S., et al. A meta-analysis of sex differences in human brain structure Neuroscience and Biobehavioral Reviews 39, (2014) 34-50

[2] Grön, G., Wunderlich, A.P., Spitzer, M., Tomczak, R. et al., Brain activation during human navigation: gender-different neural networks as substrate of performance Nature Neuroscience, 3, (2014) 404-408

Physics post: QALY – The Cost to Live

This was a blog post written as an assignment for one of my fourth year modules. QALY is something many people may not be aware of but will probably have a big impact on each of us in some way during our lifetimes.

QALY – the Cost to Live

How much is your life worth? How much would you give to wake up tomorrow morning in good health, and continue to do so for the next year? Most of us would place a high price on our own and loved ones’ life and health.

However, each year NICE (National Institute for Health and Care Excellence) refuses funding for drugs which would improve and extend the lives of many patients, on a solely financial basis. NICE calculates QALYs (Quality Adjusted Life Years) for each new drug by weighting the quality of a person’s life aftertreatment, from 0 (death) to 1 (perfect health). If a treatment costs more than the threshold of £30k per QALY, NICE is likely to refuse the treatment being implemented within the NHS.

Many people would suggest this is not fair, stating that their life is surely worth more than that. (As an aside, if I were to be unfair to the NHS and NICE and perform a crude approximation, my life so far has been worth a maximum of £655,890…)

Despite this, all things must be considered in the context of the NHS as a whole. If a treatment for one patient group is recommended, another group will inevitably suffer due to re-allocation of resources. This is not to deny the pain and trauma that not having a drug will cause patients and their loved ones.

Imagine being elderly and in a hospice which is only affordable because treatment has been held back from a cancer patient.

Imagine being a mother whose child who can receive treatment for a disease because a terminally ill Grandmother has been denied the drug she needs.

Now imagine being the family of, or the patient who has been denied treatment. It’s heart-wrenching stuff.

£95,873M was the allocation to the NHS for 2013/14 [1] which seems like huge amount of money, but however much or little it is, books must be balanced. Those on the NICE committee making the decisions about whether drugs should be recommended may appear to have cold hearts, but they have to see the bigger picture. One family needing a treatment for a loved one will have tunnel vision on that; anyone would. But the budget is set and there has to be a committee to delegate funds.

Unfortunately, those do not go where we might sometimes wish they would. Hopefully it is not impossible to see at least some of the bigger picture.


[1] National Health Service Commissioning Board Annual Report & Accounts 2013-14 (pg 21)

For a summary of NICE appraisal decisions, see https://www.nice.org.uk/news/nice-statistics

Raspberry & White Chocolate Cake

This was the birthday cake requested by David with my own twists and turns.

Sponge: normal 8oz recipe , but with 2oz of the flour substituted for ground almonds, and a few handfuls of frozen raspberries mixed in right at the end. I used frozen raspberries as they would not go to smoosh when mixed into the mixture. I knew this would mean more moisture would be released from them in cooking so I made the mixture a little less wet than it would otherwise have been.

Bake as usual – they may need a little longer due to the extra liquid from the raspberries.
I put raspberry jam in the middle and then decided to experiment. I also put some fresh (defrosted..!) raspberries in the centre and for my surprise, some little macarons, as made in the previous post; see image. P1000950
This worked a treat until the cake was a 2 days old – then they were ridiculously moist. I’d suggest if you do this to not put the fresh raspberries around it, and to omit the white chocolate ganache from the middle which I then dolloped on top of the filling!
The cake was covered with white chocolate ganache and then I grated white chocolate and put glitter on the top (it’s a birthday after all!).

All in all, very tasty cake. Compliments all round!

Before I decided to spread the ganache all the way over the sides, too.
Before I decided to spread the ganache all the way over the sides, too.

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8oz Sponge recipe

8oz butter/margarine
8oz caster sugar
3 eggs
1tsp vanilla essence
8oz SR flour
1tsp baking powder

Pre-heat the oven to 180’C (170’C fan).
Cream the butter and sugar until really light in colour and combined. You can use an electric mixer, or do it by hand.
Add the 3 eggs and vanilla and mix in.
Add the dry ingredients.

Grease/line 2 9″ sandwich tins and divide the mixture between the two.

Bake for 25 mins or until they have stopped .

Leave to cool for 5mins in the tins then turn onto wire racks to cool completely before filling with jam and dusting with icing sugar.

My Victoria Sandwich
My Victoria Sandwich

Raspberry/white chocolate macarons

In Oxford the other week, we stumbled across a lovely little store on the High Street called “Pod“. There was the sweetest little book simply called “Macarons” which is by Annie Rigg . Of course, I was bought it on the condition I’d use it and that David would see the results.

A Raspberry and White Chocolate birthday cake for last week had been requested so of course I saw this as the perfect opportunity to make some accompanying macarons.

I followed the recipe in the book (200g icing sugar, 100g ground almonds, 3-4 egg whites, pinch of salt, 40g caster sugar) and then followed the instructions to a “t”. They worked! The middle was raspberry jam, and then a white chocolate ganache.
Everyone who tried them really liked them and they tasted like macarons should! Very happy!

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Coffee & Walnut Cake

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P1000850This is a yummy, easy recipe. Even people who don’t like coffee often like this. The walnuts are optional so feel free to omit them. This recipe always reminds me of the older generation for some reason!

8oz butter/margarine
8oz caster sugar
4 eggs
2tbsp Coffee essence (eg camp) or 3tsp instant coffee diluted in 2tsp hot water (adjust to taste)
8oz SR flour
1.5tsp baking powder
3oz walnuts, crushed, plus some halves for the top.

Buttercream icing, with strong instant coffee added

Cream the butter & sugar. Add the eggs and coffee flavouring – however you’ve decided to do it. I like using lots of coffee!
Add the flour and baking powder, mix it all until really smooth and then add the walnuts.

Pour into 2 greased/lined(if necessary) sandwich tins and bake at 180’C for about 20-25 mins or until they stop talking (or a skewer comes out clean).
Leave to cool for 5mins and turn out onto a wire rack.

Make the buttercream and add the coffee as you do. Again, adjust to taste.
Buttercream the sandwiches together and also put a thin layer on top. To get the classic “feathery” look on the top, drag a fork in lines down one way, then at right angles to those lines, make more lines with the fork every other fork width. (Hard to explain, sorry!)

Decorate with walnuts. And don’t eat too much at once!

Chicken in white wine and creme fraiche

This started off being based on a recipe I found. But then I just made it up. A very scrummy, healthy(ish!) meal.
Adjust quantities to tastes/no. of people. I used a lot of wine (I bought another bottle to drink, of course!), but you could substitute that for stock for a cheaper/child-friendly/different twist.

Serves 2 but so easily adjustable.
2 chicken breasts
6 shallots, peeled and halved
2 garlic cloves, crushed
8 Mushrooms, quartered
2/3 – 3/4 bottle of wine (I said I used a lot…!)
Stock (I made my own as I’d bought a chicken and butchered it)
3tbsp creme fraiche
3 bay leaves
Salt/pepper
Tarragon
Rice, to serve

Brown the chicken in some oil. Add the shallots & garlic and soften. Add the mushrooms also to soften. Remove all from the pan and add half of the wine. Boil it down for a few minutes, then replace the veg/meat to the pan. Add seasoning and bay leaves. Add a few tablespoons of stock. Keep simmering. Add more liquid as required.
Cook the rice so that it’s ready for when you want to eat.
Cook the chicken and sauce for up to an hour – this is a great one to start and then serve when people are ready to eat. If you want to thicken the sauce, sprinkle in a little plain or corn flour but make sure you boil the sauce having done this.
A couple of minutes before serving, add the creme fraiche, and remove the bay leaves. YUM! :)

You could also serve with potato.
Hope you enjoy it as much as we did!

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Banana Crumbles (I-need-dessert-crumble)

Sometimes you really fancy dessert but there just isn’t anything around. So I thought about what I have and made little ramekins of banana crumble. I’ve never had banana crumble before.

Since this made 2 ramekins, and Valentine’s day is nearly here, these could make a nice little after-dinner sweet treat. Unless you eat them both. Or hate bananas (like my Dad)!
For 2 little ramekin crumbles:

1 banana
about 20g/a knob of butter (not out of date like mine…student life)
about 20g pl. flour
about 15g brown sugar
about 20g porridge oats
a pinch of ground cinnamon
honey – optional

Chop bananas into circles and place in dish, mix the butter & flour with your fingertips and add the sugar, oats, and cinnamon. Pour and pat on top of bananas. Sprinkle a little sugar on top.
Bake in an oven at 180’C for 20ish mins or until golden on top.

I liked it with a drizzle of honey on top to compliment the banana and add sweetness. You could serve with cream, custard or ice-cream of course.

Before baking
Before baking

I write “about” and “ish” because I’m terrible at weighing things out and just shove it in until it looks about right…sorry! But it’s just a standard crumble topping.
If you like banana, I think you’ll like the different twist on a crumble. If you don’t, even the smell will probably put you off! But it does make them seem healthy!

After baking
After baking

Orange Spiced Cake

Charlotte’s birthday today, so a cake had to be made! We’ve been loving oranges in our house recently – the kitchen has been smelling good – so I thought I’d road test Mary Berry’s “Whole Orange Cake” to make a change!
Unfortunately, my scales are broken with the top having come off so some of the masses were rather guessed and so I had to adjust the recipe slightly (too much flour led to adding milk). It still turned out great though.

Here’s a link to Mary’s recipe (I was lucky enough to be able to use the recipe book itself):

I used my new silicon cake “tins” having never used them before and they worked a treat! Very impressed and saved so much hassle of fiddling around with greaseproof paper! Would definitely recommend them over loose-bottomed, having-to-be-papered tins. Although I do feel like I’m betraying my “traditional baking values” in saying that!

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I think this is going to be a great cake and a nice change from the standard variations on a Viccy Sponge!